1.25 NAPNAP Contact Hours of which 1.25 contains pharmacology content. This continuing education activity is offered free for NAPNAP Members and non-members.

This presentation synthesizes the evidence on folinic acid in autism, with an emphasis on advances since 2018 within the context of foundational work. We will examine the pathophysiology of cerebral folate deficiency (CFD), clarify genetic contributors (e.g., FOLR1 and folate-pathway variants), and review clinical testing with folate receptor-α autoantibodies and related labs. Practical treatment guidance will cover formulation selection, dosing and titration, monitoring, adverse effects, and pharmacy/compounding and cost considerations. Taught by a clinician with extensive real-world experience, the presentation highlights where the evidence is strongest and how to implement it. Learners will finish with a concise, evidence-based framework for evaluating and managing CFD in autism within standard practice.

IMPORTANT: You must be logged in using your NAPNAP Username and Password to be recognized as a Member of NAPNAP. If you are a current member of NAPNAP, and you are being asked to purchase this activity, please contact the NAPNAP National Office at (877) 662-7627 to request assistance prior to entering any payment information.    

Participants are forbidden to reproduce, republish, redistribute, or resell this course in any other form. For copyright-related questions, please email your question to: [email protected]

Copyright 2025 © by National Association of Pediatric Nurse Practitioners 

This continuing education activity is administered by the National Association of Pediatric Nurse Practitioners as an agency providing continuing education credit. Individuals who complete this program and earn a 70% or higher score on the post tests will be awarded 1.25 National Association of Pediatric Nurse Practitioners contact hours.