JPHC CE: A Review on the Use of Cystic Fibrosis Transmembrane Conductance Regulator Gene Modulators in Pediatric Patients
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Copyright © 2019 by the National Association of Pediatric Nurse Practitioners. Published by Elsevier Inc. All rights reserved.
This continuing education activity is administered by the National Association of Pediatric Nurse Practitioners (NAPNAP) as an Agency providing continuing education credit. Individuals who complete this program and earn a 70% or higher score on the post test will be awarded 1.0 NAPNAP contact hours of which 1.0 contain pharmacology content.
Keywords: cystic fibrosis, pharmacology, CFTR-modifying drugs
Pediatric-focused advanced practice registered nurses
1. Describe the six major classes of mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
2. Review the mechanisms of action of ivacaftor, lumacaftor/ivacaftor, and tezacaftor/ivacaftor.
3. Compare the indications and efficacy among the three CFTR-modifying drugs.
4. Identify the counseling points for the three CFTR-modifying drugs.
Michael Bitonti, PGY1 pharmacy resident, Department of Pharmacy, Moses H. Cone Memorial Hospital, Greensboro, NC.
Laura Fritts, PharmD candidate, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Tsz-Yin So, Pediatric Clinical Pharmacist, Department of Pharmacy, Moses H. Cone Memorial Hospital, Greensboro, NC.
Conflicts of interest: None to report.
Correspondence: Tsz-Yin So, PharmD, BCPS, Department of Pharmacy, Moses H. Cone Memorial Hospital, 1200 N. Elm
Street, Greensboro, NC 27401; e-mail: Tsz-Yin.So@conehealth.com.
- 1.00 Contact hours